6,076円 This richly illustrated book presents the latest techniques for the identifiability analysis and standard and robust regression analysis of complex dynamical models, and looks at their objectives. It begins by providing a definition of complexity in dynamic systems, introducing the concepts of sy...

10,943円 Explore Important Tools for High-Quality Work in Pharmaceutical Safety Statistical Methods for Drug Safety presents a wide variety of statistical approaches for analyzing pharmacoepidemiologic data. It covers both commonly used techniques, such as proportional reporting ratios for the analysis of...

10,612円 The concept of frailty offers a convenient way to introduce unobserved heterogeneity and associations into models for survival data. In its simplest form, frailty is an unobserved random proportionality factor that modifies the hazard function of an individual or a group of related individuals. F...

12,103円 However, exciting new developments are on the verge of changing the treatment of this debilitating disorder. Two anabolic agents, the parathyroid hormone (PTH) and the fluoride ion, show tremendous promise as tools for building and retaining bone - with no adverse side effects. Anabolic Treatment...

11,275円 Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable and non-implantable devices, rehabilitation, psychotherapy, and behavioral interventions. Unlike pharmacological treatments, these have no specific requirements for approval. Cons...

14,923円 Adaptive clinical trial designs, unlike traditional fixed clinical trial designs, enable modification of studies in response to the data generated in the course of the trial. This often results in studies that are substantially faster, more efficient, and more powerful. Recent developments in web...

15,800円 This book discusses a multidisciplinary and multi-stakeholder collaborative approach to small population clinical trials. It provides and illustrates a systematic framework that depends upon a collaborative infrastructure between the patient community, patient advocacy groups, researchers and inv...

10,943円 Useful Statistical Approaches for Addressing Multiplicity Issues Includes practical examples from recent trials Bringing together leading statisticians, scientists, and clinicians from the pharmaceutical industry, academia, and regulatory agencies, Multiple Testing Problems in Pharmaceutical Stat...

1,326円 Stay away from sushi! Cut out caffeine! Get rid of your cat! Step away from the microwave! Pregnant women are bombarded with "risk factors" they must avoid from the moment the stick turns pink. Heroic mothers-to-be sacrifice their favorite foods and activities for the sake of their baby, but with...

8,124円 Today, scientists are expected to be more accountable and transparent than at any other time in history. Globally, the pursuit of knowledge creation enjoys a place of distinction, and the public expects to reap considerable benefits from the innovative contributions made by researchers. It is, th...

12,269円 Introduction to Regression Methods for Public Health Using R teaches regression methods for continuous, binary, ordinal, and time-to-event outcomes using R as a tool. Regression is a useful tool for understanding the associations between an outcome and a set of explanatory variables, and regressi...

10,943円 With new statistical and scientific issues arising in adaptive clinical trial design, including the U.S. FDA's recent draft guidance, a new edition of one of the first books on the topic is needed. Adaptive Design Methods in Clinical Trials, Second Edition reflects recent developments and regulat...